What Is 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7? Specifications, Uses, and Sourcing Information

3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid, identified by CAS Number 376592-93-7, is an aromatic carboxylic acid containing a biphenyl structure, an amino group, and a hydroxyl group. I supply this compound as a specialty chemical and pharmaceutical intermediate for research, process development, and downstream synthesis, subject to agreed specifications and documentation. Its commonly represented molecular formula is C₁₃H₁₁NO₃, with a calculated molecular weight of approximately 229.23 g/mol. Because published commercial specifications can vary by supplier and intended use, I recommend confirming identity, assay, residual solvents, and packaging requirements before placing a purchase order.

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Direct Definition and Chemical Identity

The name describes the substitution pattern on a biphenyl core. The molecule contains two aromatic rings connected by a single carbon-carbon bond, together with a carboxylic acid group, an amino group, and a phenolic hydroxyl group. These functional groups provide several chemically relevant sites for further transformation, but the actual reactivity depends on reaction conditions, protection strategy, solvent, temperature, and the quality grade selected.

CAS 376592-93-7 should be used as the primary identifier during supplier communication because similar aromatic intermediates may have closely related names. I recommend comparing the CAS number with the molecular formula, molecular weight, structural drawing, and analytical data shown on the specification sheet. Buyers should also verify whether the material is being purchased for laboratory research, route scouting, scale-up, or regulated manufacturing.

Core Functions and Chemical Value

Aromatic Intermediate for Further Synthesis

In synthetic chemistry, this compound can serve as a multifunctional aromatic building block. The carboxylic acid may participate in esterification, amidation, or other carboxyl-group transformations, while the amino group can be used in coupling, acylation, or protection reactions. The phenolic hydroxyl group may also influence solubility, hydrogen bonding, and selectivity during downstream processing.

I do not describe the material as a finished active pharmaceutical ingredient. It is more appropriately evaluated as a research chemical or pharmaceutical intermediate unless the buyer has completed the required route qualification, impurity assessment, process validation, and regulatory review. This distinction is important when purchasing for commercial development.

Structure-Driven Development Potential

The combination of three functional groups on a biphenyl framework may be useful when a development program requires controlled modification of aromatic polarity or molecular architecture. However, the presence of multiple reactive groups can also create competing reactions or affect crystallization behavior. For this reason, I recommend small-scale compatibility testing before committing to a large production quantity.

Application Scenarios

Potential applications include medicinal chemistry research, intermediate screening, custom synthesis, process development, and preparation of more complex aromatic compounds. Research teams may evaluate the material in parallel synthetic routes where an amino-hydroxy-carboxylic acid framework is required. Contract manufacturers may also use it as a defined starting material after confirming that the proposed process is compatible with the delivered grade.

The compound may be relevant to pharmaceutical intermediate development, but its suitability is project-specific. A buyer should not assume that a research-grade lot is automatically suitable for GMP manufacturing or clinical production. I support customers by discussing intended use, required analytical package, expected scale, and documentation before quotation.

• Research and route scouting: suitable documentation and a practical sample quantity are often the first priorities.
• Process development: batch consistency, impurity profile, solubility, and reproducible packaging become more important.
• Commercial sourcing: buyers should assess manufacturing capacity, quality agreements, change-control procedures, and supply continuity.
• Custom synthesis: reaction feasibility, raw-material availability, and target specifications should be reviewed before development begins.

Types, Grades, and Material Options

Suppliers may offer this chemical in different commercial arrangements rather than in completely different chemical forms. Typical distinctions include research quantity, development quantity, and larger production-oriented supply. The relevant differences may involve assay range, impurity limits, analytical documentation, packaging configuration, and whether the batch is produced to a customer-approved specification.

I recommend selecting the grade according to the next process step rather than choosing the lowest quoted price. A material for early route screening may require identity confirmation and a basic assay, while a material for a validated process may require a more detailed certificate of analysis, residual solvent data, elemental impurity information, and defined retest or storage conditions. The exact package should be agreed in writing.

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Key Specifications Buyers Should Review

The following information provides a practical starting point for technical evaluation. The values shown for formula and molecular weight are structure-based reference data, while release limits must be confirmed against the supplier’s current specification and batch certificate. I avoid presenting an unverified assay or appearance value as a universal standard because commercial requirements differ by application.

For a first evaluation, buyers commonly request a sample in the gram range, but the appropriate quantity depends on the planned experiments and internal testing method. I can discuss sample sizes such as 1 g, 5 g, or another agreed amount without implying that every project requires the same quantity. Larger orders should be quoted according to specification, packaging, production schedule, and destination.

Buyer Selection Factors

Identity and Analytical Evidence

I recommend requesting a current certificate of analysis, analytical spectrum or chromatogram where available, and a specification sheet before approval. The buyer’s quality team should compare the reported data with the intended structure and internal acceptance criteria. If the compound is critical to a regulated route, the analytical package should be reviewed by the customer’s qualified technical and quality personnel.

Supply Continuity and Batch Control

Price alone does not show whether a supplier can support a development program. I encourage buyers to ask about production location, standard batch size, lead-time assumptions, packaging, lot traceability, and the process for handling specification changes. A practical supply plan should distinguish sample availability from routine production availability.

Storage and Transport Requirements

The supplier should provide handling and storage guidance based on available stability information and packaging design. Buyers should confirm whether the material requires protection from moisture, heat, light, or contamination during transport and warehouse storage. I recommend using the supplier’s safety data sheet and product-specific instructions rather than applying a generic condition without verification.

How Maison Chemical Supports Sourcing

At Maison Chemical, I approach this product as a B2B sourcing project rather than a simple catalog transaction. I can help clarify the required quantity, intended application, specification level, packaging format, and destination before preparing a quotation. For qualified inquiries, I can also coordinate the relevant technical documents and discuss whether a sample, development batch, or larger production order is the right next step.

My support is designed for pharmaceutical intermediate buyers, research organizations, chemical distributors, and contract development teams. I use conservative communication when a requirement has not yet been confirmed, particularly for purity targets, lead time, storage conditions, and regulatory documentation. This helps reduce the risk of selecting a material that is chemically correct but operationally unsuitable for the customer’s process.

Key Takeaways

• 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid is a multifunctional aromatic intermediate with CAS Number 376592-93-7.
• The commonly represented formula is C₁₃H₁₁NO₃, and the calculated molecular weight is approximately 229.23 g/mol.
• Its amino, hydroxyl, and carboxylic acid groups may support further synthetic transformations, but route suitability must be tested.
• Assay, impurities, residual solvents, water content, packaging, and documentation should be agreed before purchase.
• A research-grade sample should not automatically be treated as suitable for regulated or commercial manufacturing.

Conclusion and Next Steps

In direct answer to the question, 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7 is a specialized biphenyl-based aromatic carboxylic acid used primarily as a research and pharmaceutical intermediate. Its value comes from the combination of amino, phenolic hydroxyl, and carboxylic acid functionality, which can support further chemical development. The correct purchasing decision depends on verified identity, batch quality, intended synthesis, and the documentation required by the buyer.

For the next step, I recommend sending Maison Chemical your target quantity, desired assay or impurity limits, application stage, packaging preference, destination, and documentation requirements. I can then help determine the appropriate supply option and provide a quotation based on the confirmed specification. Contact Maison Chemical for a product discussion, sample assessment, or B2B sourcing proposal for CAS 376592-93-7.

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