3-Carboxyphenylboronic Acid CAS 25487-66-5: Specifications, Uses, and Supplier Guide

If you are sourcing 3-Carboxyphenylboronic acid, CAS 25487-66-5, I recommend evaluating three points first: confirmed identity, application-specific quality requirements, and the supplier’s ability to provide consistent documentation and delivery. This compound is also commonly described as 3-boronobenzoic acid or 3-carboxyphenylboronic acid. Its molecular formula is C₇H₇BO₄, and its calculated molecular weight is approximately 165.94 g/mol. I use these identifiers as the starting point for quotation, technical review, sample approval, and production planning.

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In this guide, I explain what the material is, where it is used, which specifications buyers should request, and how to compare potential suppliers. Because final requirements vary between medicinal chemistry, process development, and research applications, I advise confirming the current specification with the supplier before placing an order. Maison Chemical can support buyers with product information, quotation review, sample coordination, and application-oriented sourcing discussions.

Key Takeaways for Buyers

• 3-Carboxyphenylboronic acid is an aromatic boronic acid bearing both a carboxylic acid group and a boronic acid group.
• CAS 25487-66-5, molecular formula C₇H₇BO₄, and molecular weight approximately 165.94 g/mol should be checked against the supplier’s documentation.
• Its principal value is as a building block for organic synthesis, medicinal chemistry, and research involving boronic acid chemistry.
• Buyers should assess assay, identification, water content, residual solvents, packaging, batch consistency, and regulatory documentation rather than relying on a name alone.
• Maison Chemical provides a practical sourcing route for customers seeking a dependable pharmaceutical intermediate supplier and export partner.

What Is 3-Carboxyphenylboronic Acid?

3-Carboxyphenylboronic acid is an aromatic boronic acid intermediate with two chemically useful functional groups. The boronic acid moiety can participate in cross-coupling chemistry, while the carboxylic acid group can support further functionalization, salt formation, or incorporation into more complex molecular structures. The meta relationship between these groups is important because positional isomers can show different reactivity, synthesis behavior, and downstream performance.

For purchasing and quality control, I recommend identifying the material through multiple data points rather than CAS number alone. The usual identity set includes the chemical name, CAS number, molecular formula, molecular weight, structural representation, and an appropriate analytical identification method. A supplier should be able to provide a batch-specific certificate of analysis when the material is ordered for a controlled research or development program.

Specifications Buyers Should Review

A specification is only useful when it matches the intended application. For early-stage research, buyers may focus on identity and assay, while process development teams may require tighter controls for impurities, water, residual solvents, and batch-to-batch consistency. I suggest asking for the current product specification before comparing prices because two products with the same chemical name may be offered under different quality grades.

Analytical Documentation

I normally advise buyers to request a certificate of analysis for the relevant batch, together with the available analytical methods or method references. Depending on the supplier’s quality system and product grade, documentation may include chromatographic assay data, spectroscopic identification, water determination, and impurity information. Buyers should avoid assuming that every supplier includes the same test panel, so the requested documents should be listed clearly in the purchase discussion.

Common Applications and Application Matching

3-Carboxyphenylboronic acid is primarily used as a research and development building block. Its boronic acid functionality makes it relevant to palladium-catalyzed cross-coupling routes, including the preparation of substituted biaryl and heteroaryl structures. Its carboxylic acid group offers an additional reaction handle for amide formation, esterification, or other synthetic transformations.

In medicinal chemistry, the compound may be selected when a project requires a multifunctional aromatic intermediate that can be elaborated in more than one direction. In pharmaceutical intermediate development, it may serve as a precursor within a multistep route, although its suitability must be demonstrated under the customer’s specific reaction conditions. In academic and industrial research, it can also be used for method development, compound libraries, and exploration of boronic acid reactivity.

How I Match the Material to the Project

1. Define the reaction role. Confirm whether the material is needed for cross-coupling, carboxylic acid derivatization, or a sequential synthesis.
2. Set the quality level. Decide whether research grade, high-assay material, or a tighter project-specific specification is required.
3. Review compatibility. Check the planned solvent, base, catalyst, temperature, and purification process against the supplier’s available technical information.
4. Approve a representative sample. Use the same or comparable specification intended for larger-scale procurement whenever possible.
5. Confirm supply continuity. Discuss pack sizes, production timing, documentation, and future lot availability before scale-up.

Types, Grades, and Material Options

Suppliers may offer this compound in different pack sizes or quality levels rather than as fundamentally different chemical forms. The correct choice depends on the stage of the project, the sensitivity of the synthesis, and the amount of analytical control available at the receiving site. I recommend treating “high purity” as a starting description, not a complete specification, unless the supplier defines the assay method and acceptance criteria.

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For laboratory screening, a smaller pack can reduce inventory exposure while the route is being evaluated. For process development, a larger package may be more efficient, but only after the customer confirms that the batch documentation and material performance are acceptable. If a project requires a customized impurity limit, particle-size profile, or packaging configuration, that request should be reviewed before the quotation is finalized.

Pricing, MOQ, and Lead-Time Considerations

Pricing for 3-Carboxyphenylboronic acid can vary with quantity, specification, packaging, production status, and shipping destination. I do not recommend comparing a unit price without checking whether the quotation includes the same quality grade, analytical documents, package size, and delivery terms. A lower quoted price may not represent a lower total procurement cost if additional testing or qualification is required.

Minimum order quantity and lead time should be discussed according to the project stage. A sample or small development quantity may be available under different commercial conditions from a production-scale order. As a practical planning measure, buyers should allow time for technical review and sample approval in addition to the supplier’s stated manufacturing or dispatch period; the exact schedule must be confirmed for each order.

Supplier Evaluation Checklist

Technical and Quality Questions

• Can the supplier confirm CAS 25487-66-5 and the stated molecular formula?
• Is a batch-specific certificate of analysis available?
• Which assay and identification methods are used?
• Can the supplier discuss water, residual solvents, and related substances?
• Is the offered material suitable for research, intermediate development, or another defined use?

Commercial and Supply Questions

• What pack sizes and minimum order quantities are available?
• What is the estimated lead time for a sample and a repeat order?
• How is the material packaged for domestic or international shipment?
• Can the supplier support export documentation and destination-specific requirements?
• Is there a practical process for handling technical questions, reorders, and specification updates?

Maison Chemical approaches this product as a B2B pharmaceutical intermediate sourcing requirement rather than a simple catalog transaction. I can help buyers clarify the required grade, review the information needed for a quotation, coordinate sample discussions, and assess packaging or export needs. Any final technical or regulatory decision should remain with the customer’s qualified quality, procurement, and research teams.

Common Sourcing Mistakes to Avoid

One frequent mistake is ordering by chemical name without checking the positional isomer and CAS number. Another is accepting an assay claim without confirming the analytical basis, batch number, and accompanying impurity information. Buyers should also avoid changing suppliers or pack sizes during route development without considering whether differences in water, residual solvents, or physical form could affect the process.

It is also important not to treat a sample result as proof of long-term supply capability. Before approving a supplier, I recommend discussing repeat-order planning, documentation continuity, packaging, and communication procedures. These steps can reduce avoidable delays when a research route moves toward larger quantities.

Conclusion: How to Choose the Right Supplier

The best supplier for 3-Carboxyphenylboronic acid CAS 25487-66-5 is the one that can demonstrate correct identity, transparent specifications, suitable documentation, and a supply plan aligned with your project. The compound’s combined boronic acid and carboxylic acid functionality makes it useful for a range of synthetic applications, but actual suitability depends on the reaction route and quality requirements. I recommend starting with a written specification review, followed by sample evaluation and a clear discussion of MOQ, lead time, packaging, and repeat supply.

For your next step, send Maison Chemical the required quantity, intended application, target assay or impurity limits, destination country, and documentation requirements. I can then help structure a practical quotation and sourcing plan for your development or production needs.

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