Who This Guide Is For

This guide is intended for procurement teams, research chemists, process development groups, pharmaceutical and agrochemical manufacturers, distributors, and laboratories sourcing 3,5-Dimethylphenylboronic acid in commercial quantities. It is also useful for buyers comparing suppliers that offer different packaging, purity specifications, or documentation packages. I focus on practical purchasing decisions rather than presenting the material as suitable for every reaction or production environment.

The correct grade depends on the intended reaction, analytical requirements, scale, and regulatory expectations of the buyer. A small research project may prioritize fast availability and a suitable analytical package, while a production program may require repeatable batches, change-control communication, and defined logistics. These requirements should be clarified before requesting a formal quotation.

Basic Chemical Context

3,5-Dimethylphenylboronic acid contains an aryl boronic acid functional group and two methyl substituents positioned at the 3 and 5 locations of the aromatic ring. The boronic acid group can participate in carbon–carbon bond-forming chemistry, especially palladium-catalyzed cross-coupling with suitable aryl or vinyl halides. The exact reaction performance still depends on the reaction design, catalyst system, solvent, base, temperature, work-up, and substrate compatibility.

For identification purposes, buyers should confirm the product name, CAS number, molecular formula, molecular weight, and analytical identifiers on the supplier’s specification or certificate documents. The stated CAS number is 172975-69-8, and the commonly referenced molecular weight is approximately 149.98 g/mol. These identifiers help prevent confusion with other dimethyl-substituted phenylboronic acids or related boronic ester products.

Uses and Application Matching

Suzuki–Miyaura Coupling

The most recognizable application is use as an aryl boron reagent in Suzuki–Miyaura coupling. In this reaction family, the boronic acid may be combined with an appropriate halide or pseudohalide under a selected catalyst and base system to form a new carbon–carbon bond. I recommend that buyers evaluate the complete reaction route instead of judging the reagent only by its nominal purity.

Medicinal and Pharmaceutical Chemistry

Medicinal chemistry teams may use 3,5-Dimethylphenylboronic acid to introduce a substituted aromatic fragment into research compounds or intermediate structures. Its suitability depends on the target molecule, reaction sequence, and downstream purification requirements. For regulated development, the buyer should also confirm whether the supplier can provide the documentation needed for internal quality review and traceability.

Custom Synthesis and Process Development

Custom synthesis groups may select this material when they need a defined aryl building block for route scouting, analog preparation, or scale-up studies. During process development, useful purchasing information includes batch-to-batch consistency, packaging configuration, retest or expiry information where applicable, and the supplier’s approach to deviation communication. These details can be more important than a single headline specification.

Types, Grades, and Material Options

3,5-Dimethylphenylboronic acid should not be confused with its corresponding boronic ester, such as a pinacol ester. The acid and ester can have different handling characteristics, solubility behavior, reaction profiles, and analytical methods. A buyer should specify the exact chemical form required by the synthetic procedure rather than accepting a similar-sounding substitute.

Commercial availability may include research-scale and larger project quantities, but the exact grade, purity range, packaging, and stock position must be confirmed for each inquiry. I advise buyers to request a current product specification and a representative certificate of analysis before qualifying a new source. If the material is intended for manufacturing, the buyer should discuss whether a dedicated or repeat supply arrangement is possible.

The molecular information above supports product identification, but it does not replace lot-specific testing. Purity, water content, residual solvents, elemental impurities, appearance, and other parameters should be evaluated against the buyer’s application and quality system. Where a specification is not publicly fixed, I recommend treating it as a quotation-stage item rather than assuming a universal industry value.

Buyer Selection Framework

1. Define the Intended Use

Start by stating whether the material is for route screening, medicinal chemistry, process development, analytical work, or commercial manufacturing. The intended use determines the appropriate documentation depth and may influence the acceptable impurity profile. Providing the reaction or project context can help the supplier recommend a realistic supply option without overpromising performance.

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2. Confirm Identity and Quality Requirements

Ask for the product name, CAS number, molecular formula, molecular weight, appearance, assay or purity method, and available analytical data. Depending on the project, you may also request chromatographic data, water content, residual solvent information, or elemental analysis. I recommend agreeing in writing which parameters are release specifications and which are informational test results.

3. Review Quantity and Packaging

State the required quantity in grams or kilograms, the number of batches needed, and whether split delivery is acceptable. Packaging should protect the product during storage and transport while supporting the buyer’s handling process. Available packaging formats, inner containers, labeling, and carton configuration should be confirmed with the quotation.

4. Clarify Delivery and Documentation

Lead time is affected by stock status, production scheduling, quantity, testing, export procedures, and destination. Rather than relying on a generic delivery statement, request a current estimated lead time in calendar days and confirm whether it begins after purchase order, payment, or technical approval. For international shipments, also confirm the commercial invoice, packing list, safety documentation, and any destination-specific requirements.

Pricing, MOQ, and Lead-Time Considerations

The price of 3,5-Dimethylphenylboronic acid can vary with order quantity, purity requirement, packaging, testing, production status, and shipping destination. A low unit price may not represent the lowest total sourcing cost if it comes with extended lead time, limited documentation, or unsuitable packaging. I recommend comparing quotations on a like-for-like basis.

Minimum order quantity is not necessarily a fixed universal figure. It may differ between an in-stock research quantity and a made-to-order production quantity, so buyers should state both their immediate requirement and anticipated annual demand. For planning, a buyer may request quotation options for 10 g, 100 g, and 1 kg, but these quantities are examples for comparison and must be confirmed with the supplier.

Lead-time planning should include time for technical review, quality approval, production, testing, export preparation, and transportation. If the project has a fixed campaign date, I suggest requesting a staged supply plan rather than waiting until the final production requirement is urgent. Early communication also gives the supplier more opportunity to confirm repeat-batch feasibility.

Supplier Evaluation Checklist

• Can the supplier confirm CAS 172975-69-8 and the exact chemical form?
• Are the molecular formula and molecular weight consistent with the requested material?
• Is a current specification available for technical review?
• Can the supplier provide a lot-specific certificate of analysis when applicable?
• Are purity method, appearance, water, and residual solvent requirements clearly defined?
• Can packaging, labeling, storage, and transport conditions be documented?
• Are MOQ, stock status, lead time, and quotation validity stated clearly?
• Can the supplier support repeat orders and communicate material or process changes?

A supplier should be evaluated on technical communication as well as price. Clear answers about what is tested, what is guaranteed, and what remains subject to confirmation reduce qualification risk. Buyers should also check whether the supplier’s documents match the requirements of their own quality, regulatory, and import teams.

How Maison Chemical Supports B2B Inquiries

At Maison Chemical, I support inquiries for 3,5-Dimethylphenylboronic acid by reviewing the requested quantity, application, target specification, packaging, destination, and delivery schedule. I can help organize the information needed for a practical quotation, while keeping product claims tied to available documentation. This approach is intended to help buyers distinguish confirmed data from items that still require lot-specific verification.

For a more efficient quotation, please include the CAS number, required quantity, desired grade or purity, packaging preference, destination country, target delivery date, and documentation requirements. If you are qualifying the material for a new route, it is also useful to state whether you need research-scale material, process-development quantities, or repeat commercial supply. I can then review the request and confirm current availability, MOQ, lead time, packaging, and document options.

Key Takeaways

• 3,5-Dimethylphenylboronic acid is an aryl boronic acid identified by CAS 172975-69-8.
• Its commonly referenced molecular formula is C₈H₁₁BO₂, with a molecular weight of approximately 149.98 g/mol.
• Its principal value is as a building block and coupling reagent, especially for suitable Suzuki–Miyaura reactions.
• Buyers should distinguish the boronic acid from related boronic esters and other positional isomers.
• Purity, analytical methods, packaging, MOQ, lead time, and documentation should be confirmed for the specific order.

Conclusion and Next Steps

3,5-Dimethylphenylboronic acid CAS 172975-69-8 can be a practical aryl building block for synthetic chemistry, but the right purchase decision depends on more than the product name. I recommend confirming identity, application fit, lot-specific quality information, packaging, MOQ, lead time, and documentation before approving a supplier. This is especially important when moving from laboratory screening to process development or repeat manufacturing supply.

To request a quotation from Maison Chemical, send your required quantity, specification, delivery destination, target schedule, and documentation needs. I will use those details to help confirm the most appropriate available supply option and identify any points that require technical or quality review before order placement.