What Is 2,6-Bis(benzyloxy)pyridine-3-boronic Acid CAS 2096339-92-1?

2,6-Bis(benzyloxy)pyridine-3-boronic acid, identified by CAS 2096339-92-1, is an aromatic heterocyclic boronic acid used primarily as a research and synthetic building block. Its structure combines a pyridine ring, two benzyloxy substituents, and a boronic acid group. I classify it as a protected, multifunctional pyridyl boronic acid rather than as a finished active ingredient or a general-purpose industrial chemical. For procurement, I recommend confirming the current specification, analytical data, packaging, and intended use with the supplier before placing an order.

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Direct Definition and Chemical Identity

The compound contains a six-membered aromatic pyridine core with nitrogen at the ring position and a boronic acid group at the 3-position. Two benzyloxy groups are located at the 2- and 6-positions, giving the name 2,6-Bis(benzyloxy)pyridine-3-boronic acid. The boronic acid functionality is represented by B(OH)₂, while each benzyloxy group contains an oxygen-linked benzyl fragment. These structural features explain why the material may be useful in multi-step organic synthesis and medicinal chemistry research.

Based on the stated structure, the molecular formula can be represented as C₁₉H₁₈BNO₄, with a calculated molar mass of approximately 335.16 g/mol. This calculated value should be checked against the supplier’s certificate of analysis and product record, especially if the material is being registered in an internal database. CAS 2096339-92-1 is the primary identifier supplied for this specific chemical entry. I advise buyers to use both the CAS number and the full chemical name when requesting quotations to reduce the risk of product substitution.

Core Chemical Functions

Pyridine Ring

The pyridine nitrogen is a ring nitrogen that can influence electronic properties, polarity, and coordination behavior. In synthesis, a pyridyl framework can serve as a useful heteroaromatic motif for building more complex molecules. The exact reactivity depends on reaction conditions, substituents, solvent, catalyst, and the compatibility of the complete molecular structure. Therefore, I recommend treating general reaction descriptions as starting points rather than guaranteed process conditions.

Boronic Acid Group

The boronic acid group is the most prominent synthetic handle in this molecule. Aryl and heteroaryl boronic acids are commonly considered in carbon–carbon bond-forming reactions such as palladium-catalyzed Suzuki-type coupling, although the suitability of this particular compound must be established experimentally. Boronic acids can also show sensitivity to moisture, pH, storage conditions, and prolonged handling. For development work, the buyer should review assay, water content where relevant, impurity profile, and stability information instead of relying only on the product name.

Benzyloxy Substituents

The two benzyloxy groups modify the pyridine ring and may function as oxygen-containing substituents in a protected or intermediate structure. Their presence increases molecular complexity and may affect solubility, purification, crystallization, and downstream deprotection strategy. Whether the groups are retained in the final target or removed later depends entirely on the buyer’s synthetic route. I would therefore evaluate this material as a route-specific intermediate rather than assuming a universal application.

Potential Research and Application Scenarios

2,6-Bis(benzyloxy)pyridine-3-boronic acid may be considered for laboratory-scale organic synthesis, process research, medicinal chemistry programs, and the preparation of substituted heteroaromatic compounds. Its combination of a pyridine scaffold and boronic acid handle makes it potentially relevant when a project requires a functionalized heteroaryl coupling partner. It may also be used in reaction screening, route evaluation, and the preparation of advanced intermediates. These are potential uses based on its chemical structure and should not be interpreted as evidence of a validated commercial process.

In a typical research workflow, a chemist may assess the compound as a coupling substrate, compare it with alternative pyridyl boronic acids, and examine the compatibility of the benzyloxy substituents with the selected reaction conditions. The material may be especially relevant where the project needs both a heteroaromatic nitrogen and a strategically positioned boronic acid. However, the actual performance can vary with catalyst loading, base selection, reaction temperature, solvent, concentration, and work-up procedure. I recommend small-scale feasibility testing before committing to larger quantities.

Material Options and Specification Considerations

For this type of specialty intermediate, the most important “material options” are usually related to grade, quantity, packaging, and documentation rather than to different commodity forms. A buyer may request a research quantity for route screening, a larger development quantity for process studies, or a project-based supply plan for repeated synthesis. Available physical form, such as powder or solid, should be confirmed directly because appearance can vary with crystallization and handling history. The product specification should always be aligned with the intended reaction and analytical requirements.

With competitive price and timely delivery, Maison Chemical sincerely hope to be your supplier and partner.

Key Specifications Buyers Should Review

I recommend requesting a certificate of analysis for the specific lot rather than accepting a generic specification sheet alone. Useful documentation may include identity testing, assay or purity information, water-related data when applicable, residual solvent information, and chromatographic data. The analytical package should match the buyer’s quality system and intended use. If the material is for regulated development, additional documentation may be required by the buyer’s internal procedures, but these requirements should be agreed before purchase.

The calculated molar mass of approximately 335.16 g/mol is useful for laboratory calculations, but it does not replace lot-specific testing. A buyer should also confirm whether the supplier reports purity on an as-is basis, dry basis, or another defined basis. This distinction can affect weighing calculations and reaction stoichiometry. Where the product is sensitive to moisture or prolonged storage, the buyer should request practical handling guidance rather than assuming that standard room-temperature storage is suitable.

How to Select a Reliable Supply Route

Match Documentation to the Project Stage

For early discovery work, a clear identity record and suitable analytical information may be sufficient to begin screening. For process development, buyers usually need stronger lot consistency, defined packaging, repeat-order capability, and a more complete quality document package. For export or cross-border purchasing, customs information, commercial documentation, and transport conditions also become important. I suggest defining these requirements before comparing quotations so that price is not the only selection criterion.

Evaluate Quantity, Lead Time, and Continuity

Specialty boronic acids are often purchased in quantities that vary from laboratory-scale amounts to development-scale requirements. Because availability can depend on existing inventory or production scheduling, buyers should ask whether the quoted quantity is in stock, made to order, or subject to confirmation. Lead time should be provided in business days or another clearly defined unit; for example, a quotation stating 10 business days is more useful than an unqualified “fast delivery” claim. Repeated projects should include a discussion of future batch availability and change-notification expectations.

Review Technical Communication

A capable supplier should be able to confirm the product identity, available quantity, packaging, shipping destination, and documentation before order placement. Technical communication is particularly valuable when the customer needs a specific analytical method, packaging format, or import document. I also recommend asking how deviations, out-of-specification results, and product changes are handled. These questions help distinguish a transaction-only seller from a supplier prepared to support an ongoing B2B relationship.

Maison Chemical Supplier Support

At Maison Chemical, I approach 2,6-Bis(benzyloxy)pyridine-3-boronic acid as a specialty chemical sourcing requirement that needs accurate identification and practical coordination. Our role as a manufacturer, supplier, and exporter is to help customers confirm the requested CAS number, quantity, packaging, destination, and documentation needs before shipment. We can also review whether the requested specification is suitable for a research or development project, while avoiding unsupported guarantees about reaction performance. Final availability, commercial terms, and lead time should be confirmed for each inquiry.

When requesting a quotation, please provide the required quantity, target delivery country, preferred packaging, expected application, and any documentation requirements. If you need lot-specific analytical information, state that clearly so the quotation process can address it from the beginning. This information allows us to respond more efficiently and reduce avoidable clarification cycles. It also helps align the supplied material with your procurement and laboratory workflow.

Key Takeaways

• 2,6-Bis(benzyloxy)pyridine-3-boronic acid is a functionalized pyridine boronic acid identified by CAS 2096339-92-1.
• Its structure contains a pyridine ring, one boronic acid group, and two benzyloxy substituents.
• The calculated molecular formula is C₁₉H₁₈BNO₄, with an approximate molar mass of 335.16 g/mol.
• Its most credible commercial role is as a research or synthetic building block, subject to route-specific validation.
• Buyers should confirm lot-specific identity, assay, impurity data, packaging, storage guidance, lead time, and export documentation.

Conclusion and Next Steps

In direct answer to the question, 2,6-Bis(benzyloxy)pyridine-3-boronic acid CAS 2096339-92-1 is a specialized heteroaromatic boronic acid intermediate designed for consideration in organic synthesis and research applications. Its pyridine nitrogen, boronic acid coupling handle, and two benzyloxy substituents give it a distinctive multifunctional structure. The compound should be selected according to the buyer’s synthetic route and documentation requirements, not simply by name or price.

The next practical step is to send Maison Chemical your required quantity, destination, specification expectations, and intended research stage. We can then confirm current supply information, available analytical documentation, packaging, and delivery terms. Before scale-up, I recommend evaluating a representative lot under your own reaction and purification conditions. This approach supports a more reliable purchasing decision while keeping technical and commercial expectations clearly defined.

Contact us to discuss your requirements of 2,6-Bis(benzyloxy)pyridine-3-boronic acid CAS 2096339-92-1. Our experienced sales team can help you identify the options that best suit your needs.